Dark lip
Conditions
Interventions
Picosecond 532 nm Nd:YAG,
Zoom HP
Endpoint: Greyish to immediate whitening
Experimental Device
Picosecond 532 nm Nd:YAG by PicoWay®,
Syneron Candela,
Sponsors
Institute of Dermatology, Department of medical services
Ministry of public health
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Age over 18 year-old 2.Fitzpatrick skin types IV-V 3.Able to attend every appointment assigned 4.Willing to participate in the study and signed the inform consent
Exclusion criteria
Exclusion criteria: 1.Presence of disease or condition such as fixed drug eruption, Pigmented contact dermatitis, discoid lupus erythematosus of the lips, Lichen planus of the lips, Labial lentigines, Peutz-Jegher syndrome, Addison’s syndrome 2.Pregnancy or lactation 3.Previously treated with energy base devices within 3 months 4.Previously treated with topical bleaching agents within 1 month 5.Active skin infection or dermatitis around the treated area 6.History of tattooing with pink or red color 7.Current smoking 8.Systemic retinoid within the past 6 months 9.Heavy sun exposure 10.Currently on systemic treatment: Hydroxychloroquine, Clofazimine, Zidovudine, Minocycline
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percent change in melanin index Week 0, week 4, week 8, week 12, week 24 Mexameter ®MX 18 spectrophotometer | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement scale week 4, week 8, week 12, week 24 Rating scale by blinded dermatologists,Patient satisfaction Week 24 Patient satisfaction rating scale,Adverse effects Week 0, week 4, week 8, week 12, week 24 Evaluated from patients and attending dermatologists | — |
Countries
Thailand
Contacts
Public ContactTanaporn Borriboon
Institute of Dermatology
Outcome results
None listed