A randomized control trial of Hyoscine N-Butylbromide versus Lidocaine pretreatment for alleviating pain onÂ propofolÂ injection

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20201207002

Enrollment

Unknown

Registered

2020-12-07

Start date

2020-04-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain on propofol injection pain&#44

Interventions

hyoscine 20 mg + NSS up to 3 ml intravenous injection after tourniquet via sphygmomanometer at 60 mmHg Duration 60 seconds,2% lidocaine without adrenaline 3 ml (60 mg) intravenous injection after tour

Experimental Drug,Active Comparator Drug

hyoscine,Lidocaine

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age 18-60 years old ASA physical status I-II

Exclusion criteria

Exclusion criteria: Refused to participation Be Allergic to Lidocaine or Hyoscine Prior analgesia, antimuscarinic drug or anti-inflammatory drugs before surgery Chronic pain Diabetes mellitus Unable to communicate/evaluate NRS Contraindication for hyoscine -Glaucoma -Gut obstruction or ileus -BPH with urinary retention -Myasthenia gravis -Angina -Heart failure

Design outcomes

Primary

Measure	Time frame
pain score on propofol injection at the time of propofol injection Visual analogue scale	—

Secondary

Measure	Time frame
the side effect of hyoscine after release tourniquet heart rate	—

Countries

Thailand

Contacts

Public ContactIsarapong Kochhirun

Faculty of Medicine, Khon Kaen university

isarapong@kkumail.com+66897122107

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026

A randomized control trial of Hyoscine N&#45;Butylbromide versus Lidocaine pretreatment for alleviating pain onÂ propofolÂ injection