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Comparative study of surgical site infection with or without post cesarean prophylactic oral antibiotics; a single-blinded randomized clinical trial

Study of surgical site infection with or without prophylactic oral antibiotics

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20201204002
Enrollment
462
Registered
2020-12-04
Start date
2019-12-02
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ُSurgical site infection was assessed Superficial&#44

Interventions

cefalexin 500mg every 6 hours and clindamycin 300 mg every 6 hours up to 48 hours after the second day after cesarean section ,Control group did not take any medication out of routine drugs
Active Comparator Drug,Active Comparator Drug
cefalexin and clindamycin,cefazolin

Sponsors

Urmia University of Medical Sciences
Lead Sponsor
Urmia University of Medical Sciences
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: All participants with emergency cesarean section, satisfied to participate without any sensitivity to antibiotics.

Exclusion criteria

Exclusion criteria: Exclusion criteria were receiving antibiotics in addition to routine cefazolin, intraoperative atony event, placenta previa, decolonization, massive bleeding leading to blood transfusion, BMI> 35 kg/m2, taking immunosuppressive drugs and corticosteroids, known underlying diseases including autoimmune, lymphoblastic, rheumatological and cardiac diseases, elective cesarean section, febrile patients at the time of hospitalization

Design outcomes

Primary

MeasureTime frame
Incidence of surgical site infection start of the project, visit on day 7-10 and follow-up on day 30. Observation

Secondary

MeasureTime frame
HbA1C start of the project, visit on day 7-10 and follow-up on day 30. Blood sample

Countries

Iran

Contacts

Public ContactShabnam Vazifekhah

Urmia University of Medical Sciences

shabnamvazifekhah1985@gmail.com00984332234897

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026