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Prediction of Fluid Responsiveness by Measuring the Effect of Lung Recruitment Maneuver to Perfusion Index in Mechanically Ventilated Patients During Surgery

Prediction of Fluid Responsiveness by Measuring the Effect of Lung Recruitment Maneuver (RM) to Perfusion index (PI) in Mechanically Ventilated Patients during Surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20201202001
Enrollment
32
Registered
2020-12-02
Start date
2020-12-14
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients older than 18 yr who scheduled for elective non-laparoscopic surgery Elective surgery, fluid responsiveness, Perfusion index and recruitment maneuver

Interventions

PI will be recorded before and after lung recruitment maneuver (application of continuous positive airway pressure of 30 cm H2O for 30 s) then SV will be measured before and after volume expansion
during 10 min)
Experimental Device
PI reduction after RM

Sponsors

Faculty of Medicine Ramathibodi Hospital, Mahidol University
Lead Sponsor
Faculty of Medicine Ramathibodi Hospital&#44
Collaborator
Mahidol University
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: - Elective surgery - Equipped with a radial arterial catheter and cardiac output monitor

Exclusion criteria

Exclusion criteria: -Arrhythmia, preoperative lung disease, left ventricular ejection fraction less than 50%, possible right ventricular dysfunction due to sleep apnea/severe chronic obstructive pulmonary disease/pulmonary hypertension - Intracranial hypertension, Hemodynamic unstable - Laparoscopic surgery

Design outcomes

Primary

MeasureTime frame
Sensitivity and specificity of PI reduction after RM to predict preload responsiveness within 10-15 minute (after fluid challenge) Perfusion index reduction after recruitment maneuver—

Secondary

MeasureTime frame
Sensitivity and specificity of PVI and PVI change to predict preload responsiveness within 10-15 minute (after fluid challenge) Pleth variability index (PVI)—

Countries

Thailand

Contacts

Public ContactSunthiti Morakul

Department of Anesthesiology Faculty of Medicine Ramathibodi Hospital, Mahidol University

sunthiti@hotmail.com66818544179

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026