Lidocaine for reducing pain from intravenous Nefopam infusion

An intravenous Lidocaine bolus for reducing pain from intravenous Nefopam infusion

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20201125006

Enrollment

Unknown

Registered

2020-11-25

Start date

2020-03-06

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain from nefopam injection pain&#44

Interventions

intravenous lidocaine injection,NSS

Active Comparator Drug,Placebo Comparator Drug

lidocaine ,nss

Eligibility

Sex/Gender

All

Age

20 Years to 80 Years

Inclusion criteria

Inclusion criteria: General Patient age 20-80 years old who was schedile for an elective surgery at King Chulalongkorn Memorial Hospital with a plan for regional anesthesia (Neuraxial/peripheral anesthesia)

Exclusion criteria

Exclusion criteria: 1. Patient allergy to any medication used in the study 2. Patient unable to state or understand VAS score 3. Patient who had previous experience with nefopam 4. Patient with Chronic pain 5. Patient who was having medication which increase Serotonin level

Design outcomes

Primary

Measure	Time frame
pain from nefopam decreased with lidocaine infusion 5 minutes VAS pain score	—

Secondary

Measure	Time frame
pain from nefopam decreased with lidocaine infusion 1, 10 and 15 minutes VAS pain score	—

Countries

Thailand

Contacts

Public ContactMarvin Thepsoparn

Chulalongkorn University

Marvin.thep@gmail.com+66858131830

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026