CMV colitis Stool CMV PCR,
Conditions
Interventions
Collection of stool of eligible patients for testing of CMV PCR
Experimental Procedure/Surgery
Stool CMV PCR
Sponsors
Faculty of Medicine Siriraj Hospital
Gastroenterology Division,
Faculty of Medicine Siriraj Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Age > 18 year old 2. Patients who meet one of criteria in both 2.1 and 2.2 2.1)Patients at risk of CMV infection - HIV infection - Post organ transplant - Hematologic malignancy - Immunosuppressive agents - Chemotherapeutic agents - Advanced age with multiple co-morbidities - Critically ill-patients 2.2) Patients present with symptoms suspicious CMV clolitis - Abdominal pain - Diarrhea - LGIH - Ileus - Bowel perforation
Exclusion criteria
Exclusion criteria: Patients who cannot proceed colonoscopy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Accuracy of stool CMV PCR in diagnosis of CMV colitis compared with tissue pathology at dignosis of CMV colitits Senstovity, specificity, accuracy of stool CMV PCR | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation of quantitative stool CMV PCR and serum CMV viral load with tissue pathology at diagnosis of CMV colitis quantitative stool CMV PCR, serum CMV viral load,Association of quantitative stool CMV PCR to mortality rate, surgical rate, curative rate after diagnosis of CMV colitis to complete treatment quantitative stool CMV PCR, mortality rate, surgical rate, curative rate | — |
Countries
Thailand
Contacts
Public ContactJulajak Limsrivilai
Division of Gastroenterology , Faculty of medicine, Siriraj hospital
Outcome results
None listed