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A randomized control trail study of preoperative oral carbohydrate loading affect to postoperative insulin resistance in bariatric surgery

A randomized control trail study of preoperative oral carbohydrate loading affect to postoperative insulin resistance in bariatric surgery

Status
Recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20201106001
Enrollment
30
Registered
2020-11-06
Start date
2020-11-03
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Morbid obesity patient Morbid obesity patient&#44

Interventions

Carbohydrate drink in opaque glass&#44
no taste&#44
no color &#45
12.5% Carbohydrate maltodextrin 400 ml at 12 hours before anesthesia &#45
12.5% Carbohydrate maltodextrin 200 ml at 2&#45
3 hours before anesthesia ,Water drink in opaque glass &#45
Water 400 ml at 12 hours before anesthesia &#45
Water 200 ml at 2&#45
3 hours before anesthesia
Active Comparator Dietary Supplement,Placebo Comparator Dietary Supplement
12.5% Carbohydrate maltodextrin ,Water

Sponsors

Ratchadapiseksompotch Fund, Faculty of Medicine, Chulalongkorn University
Lead Sponsor
Ratchadapiseksompotch Fund&#44
Collaborator
Faculty of Medicine&#44
Collaborator
Chulalongkorn University
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Morbid obesity patients, age between 18-70 years old and sceduled for elective bariatric surgery in King Chulalongkorn Memorial Hospital

Exclusion criteria

Exclusion criteria: Patients with gastroesophageal reflux disease Patients with Type 1 diabetes Patients with Type 2 diabetes and curret use diabetes medication Patients who current use medication that can delayed gastric emptying time Patients with psychosis

Design outcomes

Primary

MeasureTime frame
Post opertive insulin sensitivity 24,48,72 hours and 2 weeks HOMA-IR/QUICK-1

Secondary

MeasureTime frame
Inflammatory laboratory, Clinical outcome, Discomfort of patient 24,48,72 hours and 2 weeks IL6, CRP, 1st Defecate, Clinical nausea and vomit

Countries

Thailand

Contacts

Public ContactSathienrapong Chantawibul

Faculty of Medicine, Chulalongkorn University

Sathienrapong@hotmail.com0844556763

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026