The duration of action and efficacy of botulinum toxin A injection in masseteric muscle to reduce bite force in asymptomatic bruxism, A pilot study.

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20201105003

Enrollment

Registered

2020-11-05

Start date

2020-08-17

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy botulinum toxin A asymptomatic bruxism

Interventions

Volunteers receive 50 unit of botulinum toxin A injection in masseteric muscle (25 unit/side) one time

Experimental Procedure/Surgery

botulinum toxin A injection in masseteric muscle

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Healthy volunteer age â‰¥ 18 years with asymptomatic bruxism

Exclusion criteria

Exclusion criteria: Allergy to botulinum toxin A Pregnancy, Breast feeding, or postpartum within 3 months Has skin infection at masseteric area

Design outcomes

Primary

Measure	Time frame
The duration of action of botulinum toxin A injection in masseteric muscle to reduce bite force baseline, immediately after injection, 1 month, 3 month, 6 month, 12 month bite force measurement	—

Secondary

Measure	Time frame
The efficacy of action of botulinum toxin A injection in masseteric muscle to reduce bite force baseline, immediately after injection, 1 month, 3 month, 6 month, 12 month bite force measurement	—

Countries

Thailand

Contacts

Public ContactYanisorn Nanchaipruek

Faculty of Medicine Siriraj Hospital, Mahidol University

yanisorn.nan@gmail.com0946949454

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026

The duration of action and efficacy of botulinum toxin A injection in masseteric muscle to reduce bite force in asymptomatic bruxism&#44; A pilot study.