Diabetes Mellitus,
Conditions
Interventions
Participants were given 300 kcal of smoothie drink within 3-
5 minutes and blood collection after drinking at 30,
90,
180 and 240 minutes. Participants have one week wash out period before try-
out other formulas.,Participants were given 300 kcal of smoothie drink within 3-
out other formulas.
Sponsors
Faculty of Medicine Siriraj Hospital, Mahidol University
National Research Council of Thailand (NRCT)
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.people with type 2 diabetes mellitus or use blood glucose-lowering drugs more than 3 months 2.BMI > 25 kg/m^2 3.HbA1c 6.5 - 8.5 4.use stable level of blood glucose-lowering drugs and blood lipid-lowering drugs more than 3 months
Exclusion criteria
Exclusion criteria: 1.pregnancy or breastfeeding 2.people with chronic diseases or tube feeding or dysphagia i.e. pneumonia 3.people with insulin injection or use GLP-1 analogues drugs or DPP-4 inhibitors drugs 4.people with history of bariatric surgery, gastroparesis, malabsorption 5.people with history of diseases that affect blood glucose/lipid control i.e. hyperthyroidism, endocrinology and kidney disorders 6.use long-term immunosuppressants 7.cancer patient
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change from baseline Glycemia at 240 minutes Minutes after intake of each smoothie formula: 0, 30, 60, 90, 120, 180, 240 glucose (mg/dl),Change from baseline Insulin at 240 minutes Minutes after intake of each smoothie formula: 0, 30, 60, 90, 120, 180, 240 insulin (μU/ml) | — |
Secondary
| Measure | Time frame |
|---|---|
| Age Baseline years,Weight Baseline kg,็Height Baseline cm,Body Mass Index Baseline kg/m^2,Waist circumference Baseline cm,Blood pressure Baseline Systolic and Diastolic blood pressure (mmHg),Complete Blood Count (CBC) Baseline Red blood cells (RBC) [10^6 cells/ul], White blood cells (WBC) [10^3 cells/ul], Hemoglobin (HGB) [g/,glycosylated hemoglobin (HbA1C) Baseline percentage (%),liver aminotransferaces activity - Serum glutamate oxaloacetate transaminase (SGOT) Baseline Serum glutamate oxaloacetate transaminase (SGOT) [U/L],liver aminotransferaces activity - Serum glutamate pyruvate transaminase (SGPT) Baseline Serum glutamate pyruvate transaminase (SGPT) [U/L],lipid profiles concentration analysis Baseline Triglycerides (mg/dl), Cholesterol (mg/dl), HDL-Cholesterol (mg/dl) and LDL-Cholesterol (mg/dl),Creatinine concentration analysis Baseline mg/dl | — |
Countries
Thailand
Contacts
Public ContactKorapat Mayurasakorn
Faculty of Medicine Siriraj Hospital, Mahidol University
Outcome results
None listed