reduction of UVB-
Conditions
Interventions
one experimental site was randomized to treatment by alexandrite 755-
nm picosecond laser weekly for 5 sessions. Then,
follow-
up visit was scheduled at 1 and 2 months after last session. ,one experimental site was randomized to treatment by neodymium-
doped yttrium aluminum garnet (Nd:YAG) 1064-
nm picosecond weekly for 5 sessions. Then,
up visit was scheduled at 1 and 2 months after last session. ,one experimental site was randomized to no treatment which was evaluated the response every visit similar to other 2 sites.
alexandrite 755-
nm picosecond laser,neodymium-
nm picosecond,no treatment
Sponsors
Division of Dermatology, Department of medicine, Faculty of Medicine, Ramathibodi hospital
Division of Dermatology,
Department of medicine,
Faculty of Medicine,
Ramathibodi hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: aged of 18-65 years with Fitzpatrick skin type II-IV
Exclusion criteria
Exclusion criteria: had other skin diseases including active skin infection, inflammatory lesions, wound, and skin cancer currently used chemical peel, whitening agents or received laser therapy 1 month before enrollment immunocompromised patients photosensitivity or currently on photosensitizing medication.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mean relative lightness index evaluate at every visit colorimeter (DSM II ColorMeter®) | — |
Secondary
| Measure | Time frame |
|---|---|
| patient satisfaction scores evaluate at every visit visual analogue scale on satisfaction of treatment,physician improvement scores evaluate at every visit visual analogue scale on improvement of hyperpigmentation | — |
Countries
Thailand
Contacts
Public ContactVasanop Vachiramon
Faculty of Medicine, Ramathibodi hospital
Outcome results
None listed