Effectiveness of active versus receptive music therapy in patients with major depressive disorder: a pilot study

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20201103004

Enrollment

Registered

2020-11-03

Start date

2020-06-08

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major depressive disorder Major Depressive disorder&#44

Interventions

Is an evidence&#45

based clinical use of musical intervention by certified music therapist. Use many technique such as improvisation&#44

creation&#44

composition. 45&#45

minute session/week for 7 weeks,Is an evidence&#45

based clinical use of music by listening to relaxing songs&#44

for reflection and mood regulation Music have regular melody and rhythm&#44

music structured.Bonny method of guided imaginary music therapy&#44

Gamma&#45

frequency sounds (30&#45

120Hz)

Experimental Procedure/Surgery,Active Comparator Procedure/Surgery

Active music therapy ,Receptive music therapy

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.Diagnosed as Major depressive disorder by criteria DSM-V 2. MADRS score 7 or more 3. Age 18-60 years 4. Can read and understand Thai language 5. consent form was done

Exclusion criteria

Exclusion criteria: 1.severe depression ( MADRS > 34) 2. Have suicidal behavior 3. Have delusion or hallucination 4. During an electroconvulsive therapy or admission in hospital 5. Have Comorbid illnss : substance use disorder, persistent depressive disorder 6. Hearing or communication problem

Design outcomes

Primary

Measure	Time frame
Depressive symptoms Before start the intervention, after start at week 4, 7, 8,12,15,19 Montgomery Asberg Depression Rating Scale (MADRS) -thai version, Thai depression inventory (TDI) ,Depressive symptoms Before start the intervention, after start at week 4, 7, 8,12,15,19 Thai depression inventory (TDI) - client self evaluated	—

Secondary

Measure	Time frame
Anxiety symptoms Before start the intervention, after start at week 4, 7, 8,12,15,19 Hospital Anxiety and Depression Scale (Thai HADS),Daily life function Before start the intervention, after start at week 4, 7, 8,12,15,19 WHODAS 2.0	—

Countries

Thailand

Contacts

Public ContactPuthisant Tanhawarong

Faculty of Medicine, Khonkaen University

Puthta@kku.ac.th+6686 3730786

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026