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Effect of local anesthetic infiltration on postoperative pain control after laparoscopic cholecystectomy, a randomized controlled trial

Effect of local anesthetic infiltration on postoperative pain control after laparoscopic cholecystectomy, a randomized controlled trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20201103002
Enrollment
150
Registered
2020-11-03
Start date
2019-01-03
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative surgical wound pain Postoperative nausea and vomiting laparoscopic cholecystectomy local anesthetic infiltration postoperative pain

Interventions

after laparoscopic cholecystectomy was done&#44
surgical wound were closed without local anesthetic wound infiltration,after laparoscopic cholecystectomy was done&#44
all surgical wounds were infiltrated with total 10 ml of 0.5% bupivacaine into subcutaneous tissue layer,after laparoscopic cholecystectomy was done&#44
the abdominal sheath at umbilical wound was infiltrated with 5 ml of 0.5% bupivacaine&#44
then all surgical wounds were infiltrated with total 5 ml of 0.5% bupivacaine into subcutaneous tissue layer
No local infiltration,Intervention Descriptions: Local infiltration into subcutaneous tissue,Intervention Descriptions: Local infiltration into abdominal sheath and subcutaneous tissue

Sponsors

The committee for research, Faculty of medicine, Ramathibodi hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: patients receiving lapatoscopic cholecystectomy for gallbladder disease excepted malignancies

Exclusion criteria

Exclusion criteria: 1) Conversion to open cholecystectomy 2) Drainage catheter insertion

Design outcomes

Primary

MeasureTime frame
postoperative cumulative morphine consumption 24 hr after surgery milligram

Secondary

MeasureTime frame
Pain score 24 hour after surgery Numerical rating scale score

Countries

Thailand

Contacts

Public ContactApawee Tantawanit

Mahidol university

pinkpanterz@hotmail.com0805518848

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026