Antibacterial capability and postoperative pain using Self-Adjusting File and WaveOne Gold

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20201103001

Enrollment

Registered

2020-11-03

Start date

2020-09-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endodontic treatment Antibacterial capability Postoperative pain Endodontic treatment Antibacterial capability Postoperative pain Self&#45

Interventions

Patients is carried out root canal preparation using WaveOne Gold. When the file reaches the working length&#44

remove it and the root canal is irrigation with 3% NaOCl.,Patients is carried out root canal preparation using Self&#45

Adjusting File and 3% NaOCl is continuously delivered under controlled flow concomitantly to instrument operation.

Experimental Device,Experimental Device

Root canal preparation using WaveOne Gold,Root canal preparation using Self&#45

Adjusting File

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Minimum 18 years Single-canalled teeth have necrotic pulp with or without radiographic evidence of periapical radiolucency. Patients willing to participate in study.

Exclusion criteria

Exclusion criteria: Having related tooth with open apex, root fracture or resorption. Having periodontal pocket depth greater than 4 mm in related tooth Having previously undergone root canal treatment in related tooth; Having related tooth that could not be isolated with a rubber dam; Having taken analgesics 12 hours before the intervention. Having received antibiotic therapy within the previous 3 months. Diabetes, human immunodeficiency virus infection or other immunocompromising conditions.

Design outcomes

Primary

Measure	Time frame
preoperative, post-instrumentation total bacterial load At the same visit. Realtime PCR	—

Secondary

Measure	Time frame
preoperative, post-instrumentation pain 1 week Visual analog scale (VAS) 0-100mm	—

Contacts

Public ContactKHOA PHAM

University of Medicine and Pharmacy Hochiminh city, Vietnam

khoapham1971@gmail.com+84772000300

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026

Antibacterial capability and postoperative pain using Self&#45;Adjusting File and WaveOne Gold