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Effects of Recombinant Human Erythropoietin on Patient Survival Rate during Severe Sepsis

Effectiveness and Safety of Recombinant Human Erythropoietin on Patient Survival Rate during Severe Sepsis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20201022004
Enrollment
300
Registered
2020-10-22
Start date
2020-06-30
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis Anemia Erythropoietin Sepsis Survival rate

Interventions

Sepsis patients who received erythropoietin,Sepsis patients who did not received erythropoietin
Treatment,Treatment
EPO group,non&#45

Sponsors

None
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1.Participants who admitted to intensive care unit due to sepsis/ septic shock. 2.Participants who age of 18 years or older with received erythropoietin according to their underlying disease.

Exclusion criteria

Exclusion criteria: 1. Participants with missing clinical and laboratory data. 2. Participants who have been referred to another hospital. 3. Participants who have been treated with alternate to standard sepsis bundle scheme for sepsis and/or septic shock treatment as described in sepsis management guidelines.

Design outcomes

Primary

MeasureTime frame
Survival rate 29 days Kaplan-Meier Analysis

Secondary

MeasureTime frame
The total dose of inotropic drugs requirement (cumulative dose) during septic shock, adverse effects 29 days Vasopressor dependency index ,Percentage of patients receiving red-cell transfusion During day 1-29 Number of patients receiving red-cell / total number of patients in the study arm.,Change of hemoglobin concentration from baseline During day 1-29 Hb at day 29 - Hb at day 1,Adverse effects from EPO treatment During day 1-29 Reported symptoms

Countries

Thailand

Contacts

Public ContactWiwat Chancharoenthana
wiwat.cha@mahidol.ac.th023549168

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026