Evaluation of safety and effect of food supplement from Polyphenol-Rich Herbal Congee on working memory and cognitive processing in elderly volunteers

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

TCTR

Registry ID

TCTR20201020003

Enrollment

Registered

2020-10-20

Start date

2021-01-26

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy conditions tomato pomace congee elderly parkinson&#039

Interventions

Subjects are received the placebo product which has same color and smell look like herbal congee combined with extract of tomato pomace,Subjects are received herbal congee combined with extract of tom

Placebo Comparator Dietary Supplement,Experimental Dietary Supplement,Experimental Dietary Supplement

Placebo,Herbal Congee combined with extract of tomato pomace 200 mg/day,Herbal Congee combined with extract of tomato pomace 400 mg/day

Eligibility

Sex/Gender

All

Age

60 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1.Aged between 60-70 years old 2.Blood pressure <140/90 mmHg and fasting plasma glucose <126 mg/dL

Exclusion criteria

Exclusion criteria: 1.Volunteers who have been diagnosed with cardiovascular diseases, respiratory diseases, neuropsychological diseases, head injury, diabetes mellitus, liver disease, cancer, autoimmune diseases and hematological disorder 2.Volunteers who require supplements or herbs or drugs at least 1 months before participating in this study 3.Volunteers who require supplements or any drug that effect on the nervous system by order of the doctor during trial 4.Smoking more than 10 pieces/day 5.Alcohol addiction

Design outcomes

Primary

Measure	Time frame
à¹ŒN100 and P300 8 weeks Event related evoked potentials (ERPs)	—

Secondary

Measure	Time frame
Computerized battery test (CDR) 8 weeks computer,Bond Ladder analogue scale 8 weeks Questionnair,Psychologucal symptom using SCL-90 questionnair 8 weeks Questionnair,Dietary questionnaire 8 weeks Questionnair,safety evaluation and side effect 8 weeks Questionnair ,Acetylcholinesterase, Monoamine oxidase (MAO), Monoamine oxidase A and B 8 weeks Elisa methods,Malondialdehyde (MDA), Superoxide dismutase (SOD), Catalase (CAT), Glutathine and peroxidase (GSP-Px 8 weeks Elisa methods,total phenolic compound 8 weeks Elisa methods,The changes of hemetalogical and clinical chemistry parameters 8 weeks laboratory ,Homocysteine 8 weeks laboratory,Alpha-synuclein and DJ-1 8 weeks ELISA Kit ,Stool examination (PH, Lactobacillus spp., Bifidobacterium spp. and Short chain fatty acid) 8 weeks laboratory	—

Measure

Time frame

Computerized battery test (CDR) 8 weeks computer,Bond Ladder analogue scale 8 weeks Questionnair,Psychologucal symptom using SCL-90 questionnair 8 weeks Questionnair,Dietary questionnaire 8 weeks Questionnair,safety evaluation and side effect 8 weeks Questionnair ,Acetylcholinesterase, Monoamine oxidase (MAO), Monoamine oxidase A and B 8 weeks Elisa methods,Malondialdehyde (MDA), Superoxide dismutase (SOD), Catalase (CAT), Glutathine and peroxidase (GSP-Px 8 weeks Elisa methods,total phenolic compound 8 weeks Elisa methods,The changes of hemetalogical and clinical chemistry parameters 8 weeks laboratory ,Homocysteine 8 weeks laboratory,Alpha-synuclein and DJ-1 8 weeks ELISA Kit ,Stool examination (PH, Lactobacillus spp., Bifidobacterium spp. and Short chain fatty acid) 8 weeks laboratory

—

Countries

Thailand

Contacts

Public ContactJintanaporn Wattanathorn

Khon Kaen University

jinwat@kku.ac.th0818721809

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026

Evaluation of safety and effect of food supplement from Polyphenol&#45;Rich Herbal Congee on working memory and cognitive processing in elderly volunteers