Due to COVID-
Conditions
Interventions
1% topical nonpreserved Methyprednisolone eyedrop apply 4 times a day for 2 weeks before surgery day, 0.9% normal saline solution eyedrop apply 4 times a day for 2 weeks before surgery day
Active Comparator Drug,Placebo Comparator Drug
Subject wtih 1% topical nonpreserved methylprednisolone acetate ,Subject with 0.9% normal saline solution
Sponsors
Ratchadapiseksompotch Fund
ืnone
Eligibility
Sex/Gender
All
Age
40 Years to 0 Years
Inclusion criteria
Inclusion criteria: 1. Age > 40 years old 2. Patient diagnosed with glaucoma with intraocular pressure at least 20 mmHg despite full medical treatment and plan to treat further with trabeculectomy. 3. able to understand protocol and condition to be volunteer and capable to visit to every appointment.
Exclusion criteria
Exclusion criteria: 1. Patients with any current intraocular infection or any history of herpes epithelial keratitis 2. Patients with current steroid treatment including every route use 3. Patients with contraindication of using topical corticosteroid or Patients with history of rising intraocular pressure after apply topical corticosteroid 4. Patients with high intraocular pressure who must have trabeculectomy within 2 weeks 5. Patients with systemic disease or any contraindication that unable to have trabeculectomy 6. Patients with pregnancy or expecting pregnancy within 1 year
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of intraocular pressure reduction after trabeculectomy 12 months proportion ot success rate | — |
Secondary
| Measure | Time frame |
|---|---|
| tear cytokine levels,relationship between tear cytokine levels and success rate 12 months Mixed model | — |
Contacts
Public ContactAratchaporn Tubtimthong
Department of Ophthalmology, Faculty of Medicine Chulalongkorn University
Outcome results
None listed