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Assessment of subclinical atherosclerosis demonstrated by coronary artery calcification in familial hypercholesterolemia patients compared with non-familial hypercholesterolemia patients

Assessment of subclinical atherosclerosis demonstrated by coronary artery calcification in familial hypercholesterolemia patients compared with non-familial hypercholesterolemia patients

Status
Recruiting
Phases
Phase 1
Study type
Observational
Source
TCTR
Registry ID
TCTR20201014001
Enrollment
70
Registered
2020-10-14
Start date
2020-09-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

familial hypercholesterolemia non&#45

Interventions

Familial hypercholesterolemia diagnosed by Dutch lipid clinic network score more than 6 points,Patients with LDL more than 130 mg/dl
Screening,Screening
Familial hypercholesterolemia,Dyslipidemia

Sponsors

Ratchadaphiseksomphot Endowment Fund
Lead Sponsor
Ratchadaphiseksomphot Endowment Fund
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1 Age > 18 years old 2 Diagnosed with definite or probable familial hypercholesterolemia by Dutch Lipid Clinic Network criteria [FH group] or LDL more than 130 mg/dl [non-FH hypercholesterolemia group]

Exclusion criteria

Exclusion criteria: 1 Secondary hypercholesterolemia eg.hypothyroidism, cholestasis, nephrotic syndrome, cushing syndrome, drug-induced 2 History of coronary artery disease, ischemic stroke 3 pregnancy 4 Have CT coronary contraindication or cannot withhold breathing during CT procedure

Design outcomes

Primary

MeasureTime frame
Coronary artery calcium score 6 months after CT scan CT coronary artery

Secondary

MeasureTime frame
Aortic valve calcium score 6 months after CT scan CT coronary artery

Countries

Thailand

Contacts

Public ContactNitipat Sandusadee

King chulalongkorn Memorial Hospital

patnitipat@gmail.com0859665982

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026