Immunogenicity of 2-dose pre-exposure intramuscular rabies vaccine co-administered with quadrivalent influenza vaccine in children

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

TCTR

Registry ID

TCTR20201013001

Enrollment

100

Registered

2020-10-13

Start date

2019-11-23

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy children aged 3-9 years Rabies vaccine Quadrivalent influenza vaccine Pre-exposure rabies vaccine administration Co-administration of pre-exposure rabies vaccine and influenza vaccine Protective level of rabies antibody

Interventions

2&#45

dose of Purified Vero Cell Rabies Vaccine (PVRV) on Day 0 and 7 and inactivated quadrivalent influenza vaccine (IIV4) on Day 0 (+/&#45

Day 28) concomitantly but in different arms,2&#45

dose of Purified Vero Cell Rabies Vaccine (PVRV) on Day 0 and 28 and inactivated quadrivalent influenza vaccine (IIV4) on Day 0 (+/&#45

Day 28) concomitantly but in different arms,Purified Vero Cell Rabies Vaccine (PVRV) only on Day 0 and 7

Active Comparator Biological/Vaccine,Active Comparator Biological/Vaccine,Active Comparator Biological/Vaccine

PVRV with IIV4 (group 1),PVRV with IIV4 (group 2),PVRV alone

Eligibility

Sex/Gender

All

Age

3 Years to 9 Years

Inclusion criteria

Inclusion criteria: Healthy children age 3-9 years old not previously received rabies vaccine prior to enrollment

Exclusion criteria

Exclusion criteria: body temperature > 38 Celsius on the day of enrollment received blood or blood products in the past 3 months vaccinated with influenza vaccine in the past 6 months

Design outcomes

Primary

Measure	Time frame
Immunogenicity of 2-dose pre-exposure intramuscular rabies vaccine 1 year rapid fluorescent focus inhibition test (RFFIT)	—

Secondary

Measure	Time frame
Immunogenicity of 2-dose pre-exposure intramuscular rabies vaccine 42 days rapid fluorescent focus inhibition test (RFFIT)	—

Countries

Thailand

Contacts

Public ContactNapaporn Chantasrisawad

Center of Excellent for Pediatric Infectious Diseases and Vaccines

ntann.ch@gmail.com0867225606

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026