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Comparison between standard dose and high dose of filgrastim for neutrophil recovery after cytarabine consolidation chemotherapy in acute myeloid leukemia patients.

Comparison between standard dose and high dose of filgrastim for neutrophil recovery after cytarabine consolidation chemotherapy in acute myeloid leukemia patients.

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20201010001
Enrollment
20
Registered
2020-10-10
Start date
2020-10-05
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The Patient aged 18 years and overand Non&#45

Interventions

The group receiving the drug Stimulated standard&#45
dose white blood cells (5 μg / kg) and CBC blood test prior to chemotherapy&#44
and CBC prescribed date on chemotherapy prescription such as CBC on 5th&#44
Day 14&#44
Day 17&#44
Day 20 and daily blood tests until neutrophil recovery &#44
with additional blood tests in addition to routine care on Day 18&#44
Day 19&#44
as investigators reviewed the treatment history of leukemia patients. Acute myeloid leukemia in the sedative phase receiving chemotherapy with cytarabine. In the past at Siriraj Hospital&#44
incidence of neutrophil recovery was more frequent during this time (filgrastim was given on the 6th day after chemotherapy was administered following the current chemotherapy regimen at Siriraj Hospi
dose white blood cells (10 μg / kg) and CBC blood test prior to chemotherapy&#44

Sponsors

Siriraj Hospital Mahidol University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Non&#45;M3 acute myeloid leukemia patients in the sedative stage who received cytarabine consolidation therapy 2. CBC had absolute neutrophil count> 1&#44;000 / μL and platelet count ≥ 100&#44;000 / μL and blast cell <5% in bone. marrow 3. Patient aged 18 years and over.

Exclusion criteria

Exclusion criteria: 1. Patients with other types of cancer or an infection that has spread into the bone marrow 2. Patients receiving immunosuppressants who also treat other diseases.

Design outcomes

Primary

MeasureTime frame
Incidence of leukocytes in patients acute myeloid leukemia receiving filgrastim 2 years Number in leukocytes patients per normal population

Secondary

MeasureTime frame
Reduce infection and side effects 2 yaers Number in infection and side effects patients in normal

Countries

Thailand

Contacts

Public ContactWeerapat Owattanapanich

Division of Hematology&#44; Department of Medicine&#44; Faculty of Medicine&#44; Siriraj Hospital&#44; Mahidol Unive

weerapato36733@gmail.com089-108-1983

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026