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Prevalence of Low Bone Mass and Sarcopenia among Thai Adults with Transfusion Dependent Thalassemia

Prevalence of Low Bone Mass and Sarcopenia among Thai Adults with Transfusion Dependent Thalassemia

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20201008006
Enrollment
Unknown
Registered
2020-10-08
Start date
2020-08-03
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Transfusion dependent thalassemia osteoporosis sarcopenia Osteoporosis osteopenia low bone mass sarcopenia bone mineral density thalassemia

Interventions

1. the onset of anemia range begins at 6&#45
24 months of age 2. requires regular blood transfusion 1&#45
2 units every 2&#45
6 weeks 3. requires iron&#45
chelating agents
Screening
Transfusion&#45
dependent thalassemia

Sponsors

Ratchadaphiseksomphot Endowment Fund
Lead Sponsor
The Thai Endocrine Society Research Grants (2563/04),The Royal College of Physicians of Thailand Grand No.5/2563,The Ratchadapiseksompotch Fund (Matching Fund), Faculty of Medicine, Chulalongkorn University, Grant No. RA-MF-43/63
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Transfusion dependent thalassemia

Exclusion criteria

Exclusion criteria: Pregnancy HIV infection Stem cell transplantation

Design outcomes

Primary

MeasureTime frame
Prevalence of Low Bone Mineral Density in Adults with Transfusion Dependent Thalassemia 3 months after complete inclusion Bone mineral density by Dexa scan—

Secondary

MeasureTime frame
Risk factor of Bone Mineral Density in Adults with Transfusion Dependent Thalassemia 3 months after complete inclusion History taking, Blood samples for hormone evaluation,Prevalence of sarcopenia in Adults with Transfusion Dependent Thalassemia 3 months after complete inclusion gait speed, hand grip, Whole body scan,Risk factors of sarcopenia in Adults with Transfusion Dependent Thalassemia 3 months after complete inclusion History taking, Blood samples for hormone evaluation,Prevalence of fragility fracture in Adults with Transfusion Dependent Thalassemia 3 months after complete inclusion History taking, morphometric vertebral fractures ,Risk factors of fragility fracture in Adults with Transfusion Dependent Thalassemia months after complete inclusion History taking, Blood samples for hormone evaluation—

Countries

Thailand

Contacts

Public ContactSuttana Sotananan

Division of Endocrinology and Metabolism, Department of Medicine, Chulalongkorn university

suttana.sotananan@gmail.com0869071144

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026