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Using a high-flow nasal cannula can maintain oxygenation and ventilation during deep sedation

Using a high-flow nasal cannula can maintain oxygenation and ventilation during deep sedation

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20201007002
Enrollment
Unknown
Registered
2020-10-07
Start date
2017-04-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients 20&#45

Interventions

Patients spontaneously breathed oxygen at 2 L/minute with a fraction of inspired oxygen (FiO2): 0.28 through a nasal cannula.,Patients administered oxygen at 60 L/minute (FiO2:0.28) through the NHF sy
Active Comparator Device,Experimental Device
Nasal cannula (NC2 group),Nasal high&#45
flow (NHF)

Sponsors

None listed

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients aged 20-80 years who were scheduled for surgery and under intravenous sedation ASA physical status 1 to 3 Avoid food and water for more than 6 hours before anesthesia Consent to the research by signing an informed consent form

Exclusion criteria

Exclusion criteria: Patients who plan for receiving other anesthesia such as spinal cord injection or a general anesthesia History of allergy to drugs used in research, such as Propofol or Fentanyl Unstable vital sign, such as hypotension Consent withheld or withdrawn

Design outcomes

Primary

MeasureTime frame
Arterial partial pressure of oxygen (PaO2) 15 minutes after propofol infusion, 15 minutes after applying oxygen By device,Perioperative interventions (airway maneuver, positive pressure ventilation, instrument insertion)) Perioperative (during operation- no specific timepoint) Event occurrence (Yes/No) ,Perioperative complication (e.g. Desaturation Upper airway obstruction) Perioperative (during operation- no specific timepoint) Event occurrence (Yes/No) ,Mouth Dryness within 24 hours post-operation Patient interview.

Secondary

MeasureTime frame
PaO2/FiO2 (PF ratio) 15 minutes after propofol infusion, 15 minutes after applying oxygen By device

Countries

Thailand

Contacts

Public ContactAmorn Vijitpavan

Ramathibodi Hospital

fluotec@gmail.com090-985-0985

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026