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The effects of amiodarone on serum apixaban level in Thai patients with atrial fibrillation

The effects of amiodarone on serum apixaban level in Thai patients with atrial fibrillation

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20201005003
Enrollment
50
Registered
2020-10-05
Start date
2020-10-05
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

less numbers of participants apixaban level interaction amiodarone

Interventions

patients recieved amiodarone with apixaban at least 7 days,patients recieved apixaban at least 7 days
Treatment,Treatment
Amiodarone with apixaban,Apixaban alone

Sponsors

Faculty of Pharmacy, Silpakorn University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age > 18 years old AF patients used apixaban at least 7 days AF patients used amiodarone at least 7 days Good compliance 100 precent Patients sign inform consent

Exclusion criteria

Exclusion criteria: Patients recieved enzyme inducer or inducer of CYP3A4, P-gp medication with apixaban that follow by ESC guideline 2018 Pregnancy and lactation patients Psychritic patient Patients were not sign inform consent

Design outcomes

Primary

MeasureTime frame
Apixaban level at 0, 3, 8 hrs 0, 3, 8 hrs apixaban กับ anti-factor Xa activity

Secondary

MeasureTime frame
correlation of apixaban and anti-factor Xa activity 0, 3, 8 hrs apixaban กับ anti-factor Xa activity

Countries

Thailand

Contacts

Public ContactPornwalai Boonmuang

Faculty of Pharmacy, Silpakorn University

boonmuang_p@su.ac.th0956519822

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026