FindTrial
Sign In

Comparison of the efficacy between Pra-Sa-Prao-Hyai powder and Loratadine in Allergic Rhinitis patients.

Efficacy and Safety of Prasaprohyai Remedy, a Thai traditional remedy compared to Loratadine in Allergic Rhinitis Patients.

Status
Active, not recruiting
Phases
Phase 1Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20201003003
Enrollment
Unknown
Registered
2020-10-03
Start date
2014-08-08
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Allergic rhinitis Allergic rhinitis&#44

Interventions

Prasaprohyai remedy consists of 21 herbal species. The major component of PSPR is Kaempferia galanga L. (rhizome) with the remaining 20 species being: Amomum testaceum Ridl. (fruit)&#44
Anethum graveolens L. (fruit)&#44
Angelica dahurica Benth. (root)&#44
Angelica sinensis (Oliv.) Diels (root)&#44
Artemisia annua L. (all parts)&#44
Atractylodes lancea (Thunb.) DC. (rhizome)&#44
Cuminum cyminum L. (fruit)&#44
Dracaena loureiri Gagnep. (stem)&#44
Foeniculum vulgare Mill. var. dulce (Mill.) Thell. (fruit)&#44
Lepidium sativum L. (seed)&#44
Ligusticum sinense Olive. Cv. Chuanxiong (rhizome)&#44
Mammea siamensis Kosterm. (flower)&#44
Mesua ferrea L. (flower)&#44
Mimusops elengi L. (flower)&#44
Myristica fragrans Houtt. (aril&#44
nutmeg and stem)&#44
Nelumbo nucifera Gaertn. (pollen)&#44
Nigella sativa L. (seed) and Syzygium aromaticum (L.) Merr. et Perry (flower&#45
bud) in equal weight each. ,Loratadine 10 mg.
Experimental Other,Active Comparator Drug

Sponsors

Faculty of Medicine, Thammasat univercity
Lead Sponsor
Center of excellence in applied Thai Traditional medicine research (CEATMR)
Collaborator

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: age in range 20 - 80 years old, diagnosed with moderate disease symptoms of allergic rhinitis (classified followed ARIA criteria), ceased using antihistamine at least 7 days before participating.

Exclusion criteria

Exclusion criteria: The patients who used nasal spray, had nasal polyp, were pregnant or lactating, had nasal septal perforations or had sinus surgery, patients with serious medical conditions such as congestive heart disease, liver and renal dysfunction, uncontrolled hypertension, severe asthma, tuberculosis, HIV were excluded.

Design outcomes

Primary

MeasureTime frame
Laboratory test Week0, 3, 6 Liver function test, renal function test, CBC, FBS, Cholesterol,Assessment Week0, 3, 6 VAS score,Minimal crossection area, Week0, 3, 6 MCA value—

Secondary

MeasureTime frame
Side effect Week0, 3,6,8 Record—

Countries

Thailand

Contacts

Public ContactWaipoj Chanvimalueng

Faculty of medicine, Thammasat university

waipoj@tu.ac.th0817334699

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026