Clinical, Radiographic, and Histological evaluation of deproteinization demineralized tooth matrix (dpDTM) as bone grafting material for alveolar ridge preservation

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

TCTR

Registry ID

TCTR20200928002

Enrollment

Registered

2020-09-28

Start date

2022-03-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Alveolar ridge preservation with dpDTM and FGG ,Alveolar ridge preservation with FDBA and FGG ,Alveolar ridge preservation with FGG

Experimental Procedure/Surgery,Active Comparator Procedure/Surgery,No Intervention Procedure/Surgery

dpDTM and FGG ,FDBA and FGG ,FGG

Eligibility

Sex/Gender

All

Age

20 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Adults patients (> 20 years old) requiring extraction of one upper or lower single root tooth (incisor, canine, and premolar) in Elien socket classification l and ll. 2. The patient can sign the consent form to participate in the study and able to follow up on the appointment. 3. Patients requiring dental implant treatment. 4.Presence of adjacent (mesial and/or distal) natural teeth. 5. Systemically healthy patients and cessation of smoking for 1 week before and 8 weeks after initial implant placement. 6. No contraindication for minor oral surgery.

Exclusion criteria

Exclusion criteria: 1. Patients with a history of malignancy, radiotherapy or chemotherapy for treatment of malignancy. 2. Pregnant patient or intending to become pregnant or nursing at the time of study inclusion. 3. Patients taking medications or having treatments with an effect on healing in general e.g. steroids, large doses of anti-inflammatory drugs, and bisphosphonates 4. Patients have an active infection in the area of study. 5. Patients have severe periodontal disease.

Design outcomes

Primary

Measure	Time frame
Dimensional change of alveolar ridge width and height immediate post operative and 3 months post operative Radiographic	—

Secondary

Measure	Time frame
The secondary outcomes were soft and hard tissue volume reductions, implant stability, and bone formation. immediate post operative and 3 months post operative. Soft tissue volume reduction with Geomagic program, Hard tissue volume reduction with ITK snap program. Implant stability with RFA, bone formation from histology and microCT	—

Countries

Thailand

Contacts

Public ContactSrisurang Suttapreyasri

Prince of Songkla University

srisurang.s@psu.ac.th0879790055

Outcome results