Saliva secretion in healthy volunteers salivation
Conditions
Interventions
A capsule contains corn starch used as placebo.,A capsule of 500 mg standardized ginger extract.,two capsules of 500 mg SGE.,Three capsules of 500 mg SGE.
0 mg SGE,500 mg SGE,1,000 mg SGE,1,500 mg SGE
Sponsors
The Faculty of Public Health
Khaosuankwang Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Be able to speak, listen, read and write in Thai, 2. Aged 18 to 60 years old, 3. Good general & oral health, 4. Non smoker and 5.Non-alcohol user
Exclusion criteria
Exclusion criteria: 1. Ginger allergy, 2. Pregnant/ breastfeeding/ having menstrual, 3. History of head & neck radiotherapy, 4. Use antithrombotic agents, antihistamines, decongestants or nonsteroidal anti-inflammatory drugs, 5. History of/ scheduled to surgery in two weeks, 6. History of gallstone or bile duct obstruction, 7. Herpes labialis infection, 8. History of recent travelling aboard, entering risk zone announced by the Ministry of Public Health, having close contact with known Coronavirus case or patient under investigation (within 14 days), 9. Body temperature higher than 37.5 Celsius with coughing, sore throat, runny nose or difficult breathing and 10. Have breakfast or meal which may alter saliva secretion
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Unstimulated saliva flow rate The primary outcome will be measured twice. Before and after taking intervention Modified Schirmer's test | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects After taking intervention Interview and observation | — |
Countries
Thailand
Contacts
Public ContactKhemakorn Wongkalasin
Khon Kaen University
Outcome results
None listed