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Chemotherapy Induced Anemia Treatment: A Randomized Clinical Trial to Compare Quality Of Life in Intravenous versus Oral Iron

Quality Of Life in patients using intravenous versus oral iron

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20200915003
Enrollment
Unknown
Registered
2020-09-15
Start date
2019-09-14
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anemia Anemia&#44

Interventions

This group received Eprex (150 units/kg subcutaneously three times a week) and Ferrous sulfate (one tablet every 8 hours) for 6 weeks,This group received Eprex (150 units/kg subcutaneously three times
intravenously at each chemotherapy session)
Active Comparator Drug,Active Comparator Drug
Eprex and Ferrous sulfate ,Eprex and Venofer

Sponsors

Shahrekord University of Medical Sciences
Lead Sponsor
Shahrekord University of Medical Sciences
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The criteria for including the study were: anemia secondary to malignancy and chemotherapy, the patient's hemoglobin 1 to 4 degrees based on the NCI system, serum ferritin level lower than 15, the Karnofsky performance status scale (an assessment tool for functional impairment) greater than or equal to 70%, and in remission stage for those cases with hematological malignancies.

Exclusion criteria

Exclusion criteria: Those patients with the following criteria were excluded: anemia due to other causes than malignancy, suffering from digestive disorders caused by oral iron intake or gastrointestinal bleeding, gastric cancer, total gastrostomy, lack of response to more than 20% of questions in the questionnaire, unwillingness of the patient to continue cooperation during the study, serum ferritin level greater than 500, patient death due to complications of the illness or treatment during the study, banning from Eprex administration due to thromboembolic events and systolic blood pressure more than 160 mm Hg during the study or any infection

Design outcomes

Primary

MeasureTime frame
Quality of life Before and after the completion of the study Using EORTC QLQ-C30, a standard questionnaire

Secondary

MeasureTime frame
Hemoglobin Before and after the completion of the study Glocometer

Countries

Iran

Contacts

Public ContactHourieh Ansari

Shahrekord University of Medical Sciences

ansari3h@gmail.com00983833330061

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026