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Effect of Green Tea Extract Loaded Chitosan Microparticles on Facial Skin: A Split-face, Double-blind, Randomized Placebo-Controlled Study

Effect of Green Tea Extract Loaded Chitosan Microparticles on Facial Skin: A Split-face, Double-blind, Randomized Placebo-Controlled Study

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20200911006
Enrollment
Unknown
Registered
2020-09-11
Start date
2016-05-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female who has clear visible wrinkles at eye corners of left and right eyes (crow’s feet) facial wrinkle green tea extract clinical study chitosan microparticle

Interventions

green tea extract encapsulated chitosan microparticles cream,Cream base
Active Comparator Other,Placebo Comparator Other
Treatment cream,Placebo cream

Sponsors

National Center for Genetic Engineering and Biotechnology
Lead Sponsor
Naresuan University
Collaborator

Eligibility

Sex/Gender
Female
Age
30 Years to 60 Years

Inclusion criteria

Inclusion criteria: Female, who denied significant medical history, age 30-60 years Having clear visible wrinkles at eye corners of left and right eyes (crow’s feet) No smoking, alcoholic and drug addiction No previous allergic reaction to cosmetic ingredients

Exclusion criteria

Exclusion criteria: Used steroid, antibiotic and antihistamine within 3 days of starting participation in the study Used topical treatment on facial skin within 3 weeks of starting participation in the study Were currently pregnant or breastfeeding

Design outcomes

Primary

MeasureTime frame
Skin elasticity 8 week Cutometer

Secondary

MeasureTime frame
Skin dullness 8 week Mexameter,Skin Wrinkle 8 week Photograph

Countries

Thailand

Contacts

Public ContactNeti Waranuch

Naresuan University

Netiw@nu.ac.th66815339002

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026