oral lichen planus superinfection oral candidiasis atrophy oral lichen planus curcumin triamcinolone
Conditions
Interventions
Eachgroups was gave either curcumin or triamcinolone acetonide by randomized
Active Comparator Drug
Curcumin,
triamcinolone acetonide
Sponsors
Faculty of Pharmacy, Princ of Sonkla University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Volunteers who were diagnosed of oral lichen planus 1.18 year old or over 2.ability to use mouthwash by ourself 3.be able to read thia lanquague 4.do not use other drug for treatment of oral lichen planus during study
Exclusion criteria
Exclusion criteria: 1.volunteers who were diagnosed of other lesions 2.taking oral route of curcumin 3.contraindication for corticosteroids, curcumin, or chitosan 4.were treatment of lichen planus within 1 month 5.no. of C. albicans is over 400 CFU/ml or oral candidiasis 6.stomatitis from other causes eg. trauma, recurrent apthous ulcer, HIV, other infectious lesions, and lichenoid reaction 7.use other mouthwash within 1 month eg. antiseptic mouthwash, analgesic drug 8.chemotherapy, radiotherapy, or immunosppressive drug within 1 monthา 9.Challacombe oral druness scale more than 4 point
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| severity and pain of lesions 4 weeks numerical scale | — |
Secondary
| Measure | Time frame |
|---|---|
| satifactory of mouthwash 4 weeks numerical scale,duration of remission stage 6 months time period | — |
Countries
Thaiand
Contacts
Public ContactKanokporn Pangsomboon
Faculty of Dentistry
Outcome results
None listed