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Periodontal Status And Gingival Crevicular Fluid Sclerostin, IL-1ß and MMP-8 Levels in Ankylosing Spondylitis

Periodontal Status And Gingival Crevicular Fluid Sclerostin, IL-1ß and MMP-8 Levels in Ankylosing Spondylitis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20200908001
Enrollment
Unknown
Registered
2020-09-08
Start date
2019-11-11
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ankylosing Spondylitis ankylosing spondylitis

Interventions

28 patients with Ankylosing Spondylitis,28 systemically healthy control subjects (C group)
Screening,Screening
Ankylosing Spondylitis patients (AS group),Systemically healthy control subjects (C group)

Sponsors

none
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: All patients with AS had been diagnosed according to the criteria of the Modified New York Criteria.

Exclusion criteria

Exclusion criteria: The exclusion criteria for AS group is; other systemic diseases in addition to AS (chronic heart diseases, diabetes mellitus, endocarditis), pregnancy or lactation, infectious diseases (hepatitis, HIV/AIDS, tuberculosis) and limited mobility. Exclusion criteria for both groups are current smokers, history of periodontal therapy during the last 6 months, and use of antibiotics at least 6 months before the study.

Design outcomes

Primary

MeasureTime frame
sclerostin levels at periodontal examinaton pg/30sec,ınterleukin-1beta levels at periodontal examinaton pg/30sec,MMP-8 levels at periodontal examinaton pg/30sec—

Secondary

MeasureTime frame
None None None—

Countries

Turkey

Contacts

Public ContactÖzlem Daltaban

Akdeniz University

daltabanozlem@yahoo.com+90 0242 310 69 69

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026