Women aged 18-45 years old Not an immunocompromised host Bacterial vaginosis treatment in previous 3 months Not taking these certain medications in the previous 1 month e.g. anti-parasitics, antibiotics bacterial vaginosis, vaginal tablet, metronidazole
Conditions
Interventions
After diagnosis of Bacterial vaginosis, the patient in this arm get 7-day course of once daily 750g-Metronidazole with 200mg-Miconazole vaginal suppository. We performed history taking, Pelvic examina
Experimental Drug,Experimental Drug
Vaginal tablet : Metronidazole 750mg and Miconazole 200 mg,2g of Oral Metronidazole
Sponsors
Faculty of Medicine Siriraj Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Women aged 18-45 years old Diagnosed Bacterial vaginosis with Amsel criteria Can avoid sexual intercourse during 7-day course of treatment in vaginal suppository group Not an immunocompromised host
Exclusion criteria
Exclusion criteria: Had Bacterial vaginosis treatment in previous 3 months Taking these certain medications in the previous 1 month e.g. anti-parasitics, antibiotics, immunosuppressants, steroids, vaginal medications, anticoagulants, disulfiram Abnormal uterine bleeding Being pregnant or lactating or having menstruation during the diagnosis and treatment Frequently perform vaginal douching Currently having sexual transmitted disease Currently on the cervical intraepithelial neoplasia treatment or cervical cancer
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| clinical cure from signs and symptoms improvement 14 days sign and symptom score,clinical cure from Amsel's criteria improvement 14 days Amsel's criteria evaluation | — |
Secondary
| Measure | Time frame |
|---|---|
| satisfaction of the treatment 14 days, 1 and 3 months satisfaction score,adverse effects of the treatment 14 days, 1 and 3 months adverse effects,Recurrence 1 month sign and symptom score at 1 month | — |
Countries
Thailand
Contacts
Public ContactManopchai Thamkhantho
Siriraj Hospital
Outcome results
None listed