Skip to content

Outcomes comparison between biportal endoscopic discectomy and open lumbar microdiscectomy for single-lumbar disc herniation; a randomized control trial

Biportal endoscopic spine surgery versus Microscopic discectomy in the treatment of single level lumbar disc herniation: a randomized controlled trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20200901003
Enrollment
64
Registered
2020-09-01
Start date
2020-09-10
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lumbar disc herniation BESS Biportal endoscopic spine surgery MD microscopic lumbar discectomy LDH lumbar disc herniation

Interventions

BESS for lumbar discectomy After general anesthesia&#44
the patients were positioned prone in a Wilson spinal frame. The operated level was identified with image intensifier and marked with surgical pen for the spinous process&#44
disc level and interlaminar space. The portal landmarks were at the lower edge of lower lamina of the upper spine and upper margin of upper lamina of the lower spine about 2 centimeters apart just lat
set the level to 2. The water pump was set to 30&#45
50 mmHg and the irrigation flow was through the skin portal. Unilateral laminotomy was performed with high speed blur and Kerrison rongeur&#44
ligamentum flavum was remove and Dural sac was exposed. For disc herniation (Figure 2.)&#44
the traversing nerve root was identified and protected with Penfield or semi tubular retractor&#44
Discectomy was done with knife&#44
curettage. Annuloplasty was done by coagulation. ,Microscopic lumbar discectomy (MD) The surgical technique was performed under general anesthesia in a prone position on a radiolucent table under fl
spinous process of the upper vertebra to the spinous process of the lower vertebra at the involved level. After creating a 3&#45
5 cm incision in the midline&#44
the fascia was dissected to the lateral edge of the inferior articular fac
Experimental Procedure/Surgery,Active Comparator Procedure/Surgery
Biportal endoscopic spine surgery for lumbar discectomy,Microscopic lumbar discectomy

Sponsors

Khon Kaen hospital
Lead Sponsor
Khon Kaen hospital
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Single level lumbar HNP patient who has 2. Neurologic claudication or radicular leg pain referring to lumbar disc herniation 3. Patient aged more than 18 years and less than 60 years old 4. MRI show single lumbar disc herniation 5. Failure of conservative treatment at least 6 weeks or severe pain not responded to conservative treatment

Exclusion criteria

Exclusion criteria: 1. Pregnancy or lactation 2. Previous history of lumbar surgery 3. Patient refuse to do surgery. 4. Medical unfit for operation 5. Spondylolisthesis more than Grade I Mayerding

Design outcomes

Primary

MeasureTime frame
VAS score for post-operative surgical site pain at PACU, 12, 24, 36, 48 and 72 hrs post-op VAS ,Morphine usage post-operative milligram

Secondary

MeasureTime frame
VAS score for back and leg pain preop and post op at 2, 12 and 24 weeks VAS,ODI score pre-op, 2 wks, 12 wks and 24 wks post-op ODI score,Macnab criteria for patient satisfaction post-op 2 weeks, 12 weeks and 24 weeks Macnab criteria ,CRP pre-op and post-op at 24 and 72 hours blood for CRP Level ,CPK pre-op and post-op at 24 and 72 hours blood for CPK level

Contacts

Public ContactThanit Foocharoen

Khon Kaen hospital

thafoo@kku.ac.th+66817244453

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026