Comparison of Clinical and Radiologic Outcomes between Oblique Lumbar Interbody fusion and Minimal Invasive Transforminal Lumbar Interbody Fusion in Spondylolisthesis : a Randomized Controlled Trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

TCTR

Registry ID

TCTR20200830001

Enrollment

Registered

2020-08-30

Start date

2020-10-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spondylolisthesis Spondylolisthesis Oblique Lumbar Interbody Fusion Minimal Invasive Transforminal Lumbar Interbody Fusion

Interventions

Incision on the side of your abdomen and carefully separates soft tissues to access the degenerated lumbar vertebrae. The damaged vertebral bone or intervertebral disc is removed. A spacer with bone g

rods and plates are inserted to keep the graft in place. The bone graft helps in bone healing and fusion of the adjacent vertebrae. Following this&#44

care is taken to reposition the soft tissues carefully and the incision is closed.,&#45

The incision is made 4 to 5 cm from the midline at the level of the facet joint to be resected/fused &#45

The soft tissue is bluntly dissected with dilators and a tablemounted tubular retractor inserted to visualize the facet joint complex &#45

Microscopic visualization gives excellent magnification and illumination. This allows identification of the inferior articulating facet &#45

Using a high&#45

speed burr&#44

the inferior facet is resected &#45

The superior facet is resected from its tip down to the superior border of the pedicle &#45

The ligamentum flavum can now be resected to expose the disc within the foramen &#45

A thorough discectomy is then performed. Cartilage from the vertebral endplates is completely removed &#45

Bone graft is packed into the anterior portion of the discectomy space &#45

A structural implant filled with additional bone graft&#44

is impacted into the discectomy space &#45

Complete insertion of implant into disc space

Experimental Procedure/Surgery,Experimental Procedure/Surgery

Oblique Lumbar Interbody Fusion,Minimal Invasive Transforminal Lumbar Interbody Fusion

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Spondylolisthesis grade 1-2 level between L2-S1 2. 1 level spinal fusion 3. Failed conservative treatment 4. Decided to participate in study

Exclusion criteria

Exclusion criteria: 1. Previous spine surgery 2. Spinal infection, tumor 3. Uncooperative 4. Can't follow up thorough study 5. Pregnant or breastfeeding patient

Design outcomes

Primary

Measure	Time frame
Leg and back pain 24 hr 1, 3, 6, 12 month after surgery Visual analogue scale ,Back pain 1 year after end of the intervention Visual analogue scale	—

Secondary

Measure	Time frame
ODI 24 hr 1, 3, 6, 12 month after surgery Oswestry LBP Disability Questionnaire Thai version,EQ-5D-5L 24 hr 1, 3, 6, 12 month after surgery EQ-5D-5L Questionnaire Thai version,Satisfaction score 24 hr 1, 3, 6, 12 month after surgery Satisfaction score ,Disc height post-op 1, 3, 6, 12 month after surgery X-ray measurement ,Foraminal height post-op 1, 3, 6, 12 month after surgery X-ray measurement ,Cross-sectional area of spinal canal 3 month MRI spine measurement ,Foramial area 12 month CT spine measurement ,Fusion status 12 month CT spine	—

Measure

Time frame

ODI 24 hr 1, 3, 6, 12 month after surgery Oswestry LBP Disability Questionnaire Thai version,EQ-5D-5L 24 hr 1, 3, 6, 12 month after surgery EQ-5D-5L Questionnaire Thai version,Satisfaction score 24 hr 1, 3, 6, 12 month after surgery Satisfaction score ,Disc height post-op 1, 3, 6, 12 month after surgery X-ray measurement ,Foraminal height post-op 1, 3, 6, 12 month after surgery X-ray measurement ,Cross-sectional area of spinal canal 3 month MRI spine measurement ,Foramial area 12 month CT spine measurement ,Fusion status 12 month CT spine

—

Countries

Thailand

Contacts

Public ContactWantanun Lorwatthanakitchai

Chulalongkorn University

wantanun.pla@gmail.com0869988951

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026