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A CREAM CONTAINING LINOLEIC ACID, 5%DEXPANTHENOL AND CERAMIDE IN THE TREATMENT OF ATOPIC DERMATITIS

A CREAM CONTAINING LINOLEIC ACID, 5%DEXPANTHENOL AND CERAMIDE IN THE TREATMENT OF ATOPIC DERMATITIS

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20200826001
Enrollment
Unknown
Registered
2020-08-26
Start date
2019-01-23
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atopic dermatitis atopic dermatitis linoleic acid urea cream

Interventions

Cream containing linoleic acid exacted from plant (sunflower oil&#44
blackcurrant seed oil&#44
balloon vine)&#44
5% dexpanthenol and ceramide 1&#44
3&#44
6 (LDC cream) LDC cream contains three major active ingredients
linoleic acid&#44
5% dexpanthenol and ceramide in the cream base which is comprised of butylene glycol&#44
glyceryl stearate&#44
disodium EDTA.,5% urea cream in the cream base which is comprised of butylene glycol&#44
disodium EDTA.
Active Comparator Drug,Active Comparator Drug
Cream containing linoleic acid&#44
dexpanthenol and ceramide (LDC),5% urea cream

Sponsors

NBD HEALTHCARE CO.,LTD.
Lead Sponsor
์N/A
Collaborator

Eligibility

Sex/Gender
All
Age
2 Years to 18 Years

Inclusion criteria

Inclusion criteria: The patients, 2 to 18 years of age with diagnosis of atopic dermatitis by using UK working party’s criteria with mild and moderate diseases were included. With regard to severity grading of SCORAD score, 0-25 scores were defined as mild diseases and 26-50 scores as moderate severity.

Exclusion criteria

Exclusion criteria: The patients with active skin infection were also excluded. The patients who have committent use of tropical or systemic corticosteroids, in addition to the loss of follow up for 2 times would be excluded from this study.

Design outcomes

Primary

MeasureTime frame
Improvement of SCORAD score Baseline, week 2, week4 measure by modified SCORAD score,Remission of atopic dermamtits week 2, week 4 improve modified SCORAD score more than 50% from baseline—

Secondary

MeasureTime frame
Improvement of skin hydration baseline, week 2, week 4 Corneometer CM 825 (Courage & Khazaka Electronic GmbH, cologne, Germany). ,Patients’ satisfaction baseline, week2, week 4 Patients’ satisfaction score from 1 to 5 score grading,Adverse effect of treatment products week 2, week4 Adverse effect record form—

Countries

Thailand

Contacts

Public ContactMontree Udompataikul

Skin Center, Srinakharinwirot University

umontree@gmail.com0816148432

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026