Side effects from magnesium e.g diarrhea,
Conditions
Interventions
Recieving Magnesium supplementation for 6 month,Recieving placebo for 6 month
Magnesium supplement,Placebo
Sponsors
Phramongkutklao hospital
Phramongkutklao hospital,
department of medicine
Eligibility
Sex/Gender
All
Age
30 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1) Age 30-60 year who have Type2 diabetes mellitus with moderately increased or severely increased albuminuria and have estimated GFR > 60 ml/min/1.73m2 2) serum magnesium level 1.6-2.4 mg/dL 3) on medications (ACEIs, ARBs) for at least 3 month
Exclusion criteria
Exclusion criteria: 1) chronic diarrhea for 3 months 2) taking medications (Proton pump inhibitor) 3) taking other magnesium supplementations e.g Milk of Magnesia, Antacids 4) Alcoholism 5) taking diuretics 6) history of small bowel surgery 7) taking vitamin D supplementation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change of albuminuria at 6th month Laboratory measurement | — |
Secondary
| Measure | Time frame |
|---|---|
| Change of Fasting plasma glucose, HbA1c, BUN, Creatinine, Lipid profile, Urine ICAM at 6th month Laboratory measurement | — |
Countries
Thailand
Contacts
Public ContactSriladda Santhitisate
Phramongkutklao hospital
Outcome results
None listed