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Efficacy of Split-Dose versus Single Dose of Ergocalciferol on Serum 25(OH)D in CAPD Patient: A Randomized Controlled Trial

Efficacy of Split-Dose versus Single Dose of Ergocalciferol on Serum 25(OH)D in CAPD Patient: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20200821005
Enrollment
Unknown
Registered
2020-08-21
Start date
2018-01-30
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

CAPD patient inclusion criteria were CAPD patient with dialysis before enrolled for at least three months&#44

Interventions

split dose group was given ergocalciferol 20&#44
000 IU on thrice a week ,ergocalciferol 60&#44
000 IU once weekly for 8 weeks
Active Comparator Drug,Active Comparator Drug
ergocalciferol 20&#44
000 IU on once a week

Sponsors

None
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: inclusion criteria were CAPD patient with dialysis before enrolled for at least three months, aged > 18 years, who were diagnosed vitamin D deficiency and insufficiency, defined by vitamin D insufficiency was of 20–29 ng/mL and deficiency was less than 20 ng/mL.

Exclusion criteria

Exclusion criteria: Subjects with history of liver diseases, patients known to have hypocalcaemia, hypercalcaemia or hyperparathyroidism, pregnant and lactating women, and history of urinary tract stone were excluded from the study. Discontinuation criteria included unwillingness to continue study, intolerable side-effects or allergy.

Design outcomes

Primary

MeasureTime frame
serum 25(OH)D concentrations 8 weeks Level of serum 25(OH)D concentrations

Secondary

MeasureTime frame
Safety profile 4 and 8 weeks Level of calcium and phosphate concentrations

Countries

Thailand

Contacts

Public ContactNaowanit Nata

Division of Nephrology, Department of Medicine, Phramongkutklao Hospital and College of Medicine

naowanitnata2017@gmail.com662-6444676

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026