End stage kidney disease Neuropathic pain Defined as neuropathic pain diagnostic questionnaire (Thai DN4) End stage renal disease Chronic kidney disease Neuropathic pain Capsicin Quality of life
Conditions
Interventions
1. Participants,
who are ESRD patients,
will do the Thai DN4 questionnaire as diagnostic criteria for peripheral neuropathy.
2. The participants will be separated into 2 arms by computer-
generated randomization.
3. The first group will use 0.075% capsicin gel to treat neuropathic pain for 8 weeks,
then wash out for 2 weeks,
then use the placebo for 8 weeks.
4. The second group will use the placebo for the first 8 weeks,
then use 0.075% capsicin gel for 8 weeks.
5. The follow up for collect data will be done at 2nd,
14th,
18th week.,1. Participants,
Sponsors
Department of Medicine, Phramongkutklao Hospital
BANGKOK DRUG CO.,
LTD
Eligibility
Sex/Gender
All
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age ≥ 20 years old 2. End stage renal disease patient 3. The scores of neuropathic pain diagnostic questionnaire (Thai DN4) are 4-8 4. Participants have moderate neuropathic pain more than 1 month 5. Participants who have been using other standard pain control pills, should take the same dose for more than 4 weeks.
Exclusion criteria
Exclusion criteria: 1. Participants who have severe side effect of 0.075% capsicin gel.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction of neuropathic pain in ESRD patient Every 2 weeks for 18weeks Visual analog score | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life Every 2 weeks for 18weeks KDQOL-SF,Characteristic of neuropathic pain Every 2 weeks for 18weeks Short-form McGill pain questionnaire | — |
Countries
Thailand
Contacts
Public ContactLt. Parinada Kittidanairuk
Phramongkutklao Hospital
Outcome results
None listed