Effects of Caspase inhibitor supplementation on reduction of human sperm DNA fragmentation increase after thawing

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

TCTR

Registry ID

TCTR20200815002

Enrollment

Registered

2020-08-15

Start date

2020-08-06

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Negative,DMSO,Caspase inhibitor

No Intervention No treatment,Active Comparator Other,Active Comparator Other

Negative control,Vehicle control,Caspase inhibitor

Eligibility

Sex/Gender

Male

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Infertile couple attending at Siriraj Infertility unit with normal semen parameters

Exclusion criteria

Exclusion criteria: Sexual transmitted infection

Design outcomes

Primary

Measure	Time frame
Sperm DNA fragmentation before and after freezing and thawing Tunel assay	—

Secondary

Measure	Time frame
Sperm motility and membrane integrity before and after freezing and thawing CASA	—

Countries

Thailand

Contacts

Public ContactAuakarn Thananyai

Faculty of Medicine Siriraj Hospital, Mahidol University

weview.panorama@gmail.com0851378160

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026