Skip to content

Comparison of 40 and 100 mg of laryngotracheal lidocaine instillation to prevent cough during emergence from general anesthesia

Comparison of 40 and 100 mg of laryngotracheal lidocaine instillation to prevent cough during emergence from general anesthesia

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20200811001
Enrollment
280
Registered
2020-08-11
Start date
2020-08-17
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cough severity during extubation compared between 40 and 100 mg of lidocaine installation through the endotracheal tube cough&#44

Interventions

Group A includes patients who will be given 2ml. (40 mg) of 2% lidocaine and 3 ml. of sterile water through a LITA tube immediately after a surgeon completes the suture,Group B includes patients who w
Experimental Drug,Active Comparator Drug
Group A,GroupB

Sponsors

Faculty of Medicine, Prince of Songkla university
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.Patient aged 18-60 years 2.American Society Anesthesiologists (ASA) classification I-IlI 3.undergo elective surgery under General anesthesia with endotracheal tube 4.operation time less than 4 hrs

Exclusion criteria

Exclusion criteria: 1.Refuse to participate the study 2.Active smoking >20 pack-years, smoking in last 1 month 3.Risk of aspiration 4.Difficult airway 5.COPD/Asthma 6.Pregnancy 7.Allergy to lidocaine propofol fentanyl cisatracurium 8.increase intracranial pressure 9.open eye surgery 10.patents who already has the tracheostomy tube

Design outcomes

Primary

MeasureTime frame
cough severity after recovery from anesthesia during extubation Minogue Scale,cough severity after recovery from anesthesia during extubation Minogue Scale

Secondary

MeasureTime frame
none none none

Countries

Thailand

Contacts

Public ContactWirat Wasinwong

Anesthesiology department, Faculty of medicine

wwasinwong@hotmail.com081-5995615

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026