postoperative scar hypertrophic scar keloid Silicone gel Onion extract Aloe vera Hypertrophic scars keloids
Conditions
Interventions
topical therapy,topical therapy
Experimental Drug,Active Comparator Drug
topical silicone gel containing onion extract and Aloe vera,silicone gel sheet
Sponsors
Skin & Health Care Co., Ltd.
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Male or female 18-60 years old 2. History of surgery 2 weeks before enrollment 3. Wound size more than 1.5 cm 4. Written informed consent to participate in the study
Exclusion criteria
Exclusion criteria: 1. Any infection 2. Any wound producing significant amount of discharge, lacking normal epithelialization, or requiring dressing after surgery 3. Any systemic diseases (e.g. diabetes mellitus, vascular disorder, autoimmune disease) 4. History of topical or systemic steroid use prior 1 month 5. Receiving immunosuppressive drug, chemotherapy, or radiation 6. History of silicone, onion extract, and Aloe vera allergies 7. Diagnosed with cancer 8.Unable to follow up according to the study protocol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of hypertrophic scar and keloid 12 weeks number of participants who develop hypertrophic scars and keloids | — |
Secondary
| Measure | Time frame |
|---|---|
| Erythema and melanin values at 4,8 and 12 week Using Mexameter,Pliability value at 4,8 and 12 week Using Cutometer,Patient and Observer Scar Assessment Scale (POSAS) score at 4,8 and 12 week Patient and Observer Scar Assessment Scale (POSAS),Patient’s satisfaction score at 4,8 and 12 week Global Satisfaction 5-rating scale | — |
Contacts
Public ContactWatsachon Pangkanon
Srinakharinwirot University
Outcome results
None listed