Helicobacter pylori positive gastritis patients Helicobacter pylori,
Conditions
Interventions
Bifidobacterium longum,Conventional PPI therapy
Experimental Drug,Active Comparator Drug
Bifidobacterium longum plus conventional ppi-
based tripple therapy,conventional ppi-
based tripple therapy
Sponsors
Chiang Mai University
Chiang Mai University
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1. 18-50 years of age. 2. Dyspeptic symptoms more than 4 weeks. 3. Endoscopy reveals Helicobacter pylori infection by rapid urease test or histology by hematoxylin and eosin staining. 4. No serious medical condition. 5. Volunteer has been instructed and is willing to provide written informed consent to participate in the study.
Exclusion criteria
Exclusion criteria: Exclusion criteria: 1. Allergy or have any contraindication to milk protein. 2. Recent use (within 4 weeks) prior to study entry of H2RAs, proton pump inhibitors or any other medication that affect acid secretion. 3. Recent use (within 4 weeks) prior to study entry of any NSAIDs, corticosteroids, anticholinergics or anticoagulants. 4. Any other conditions that the investigator feels would interfere with an endoscope and study procedure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eradication rate of Helicobacter pylori 4 weeks after enrolment percentage of negative Urease test | — |
Secondary
| Measure | Time frame |
|---|---|
| Dropout rate 4 weeks after enrolment ratio of dropout patients | — |
Countries
Thailand
Contacts
Public ContactTaned Chitapanarux
Chiang Mai University
Outcome results
None listed