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A randomized controlled study of comparison of pain score after intramuscular injection of Benzathine penicillin in female patients with syphilis among cold compression before injection,1 % Lidocaine solution and combination between cold compression before injection and 1 % Lidocaine solution

A randomized controlled study of comparison of pain score after intramuscular injection of Benzathine penicillin in female patients with syphilis among cold compression before injection,1 % Lidocaine solution and combination between cold compression

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20200803003
Enrollment
Unknown
Registered
2020-08-03
Start date
2020-07-22
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

female patients with syphilis Syphilis&#44

Interventions

cold compression 10 minutes before injection and mixed 1% lidocaine with BPG,cold compression 10 minutes before injection and mixed sterile water with BPG,mixed 1% lidocaine with BPG and compression
Active Comparator Drug,Active Comparator Other,Active Comparator Drug,Placebo Comparator No treatment
cold compression and 1% lidocaine,cold compression and sterile water, 1% lidocaine, sterile water

Sponsors

Faculty of Medicine Siriraj Hospital, Mahidol University
Lead Sponsor
Faculty of Medicine Siriraj Hospital&#44
Collaborator
Mahidol University
Collaborator

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.female patients with syphilis 2.People who can inject BPG without contraindications 3.People who can communication with Thai

Exclusion criteria

Exclusion criteria: Drug allergy : BPG or Lidocaine

Design outcomes

Primary

MeasureTime frame
pain score at during intramuscular injection, 15 minutes after intramuscular injection and 30 minutes after int Visual analog scale—

Secondary

MeasureTime frame
pain score during injection at skin and during pull the needle from skin Visual analog scale,patient satisfaction after injection 30 minutes questionnaire—

Countries

Thailand

Contacts

Public ContactPareeda Tuanwaena

Mahidol university

pareeda.ns@gmail.com0859945116

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026