oral lichen planus oral lichen planus fluocinolone acetonide oral gel 0.1% dexamethasone oral spary 0.05%
Conditions
Interventions
Spray at lesions,
three times a day,
for one month.,apply at lesions,
for one month.
Experimental Drug,Active Comparator Drug
Dexamethasone 0.05% oral spray,Fluocinolone acetonide 0.1% oral gel
Sponsors
Faculty of Dentistry, Srinakharinwirot university
Faculty of Dentistry,
Srinakharinwirot university
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Patients who have been diagnosed with atrophic or erosive oral lichen planus. 2.Not allergic to fluocinolone acetonide and dexamethasone. 3.Patient has not taken antibiotics and antifungal drug. 4.Patient has no uncontrollable diabetes or dry mouth. 5.Patient does not under systemic or topical steriods at least 2 weeks before the beginning of the study.
Exclusion criteria
Exclusion criteria: 1.Patients with dry mouth. 2.Allergic to fluocinolone acetonide 3.Allergic to dexamethasone
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Healing of oral lesion week0, week2, week4 Thongprasom's scores,Pain week0, week2, week4 Visual analog scales,Pain week0, week2, week4 Visual analog scales | — |
Secondary
| Measure | Time frame |
|---|---|
| Candida colonization week0, week2, week4 Salivary culture | — |
Countries
Thailand
Contacts
Public ContactWorawalun Hirunwidchayarat
Srinakharinwirot university
Outcome results
None listed