Locally advanced breast cancer patients Locally advanced breast cancer patients sentinel lymphnodes Sentinel lymph node biopsy indocyanine green neoadjuvant chemotherapy
Conditions
Interventions
blue dye,radio isotrope,indocyanin green
sentinel lymphnode using blue dye injection 2 ml intradermally ,Injection Tc99m dextran 0.5 mci 0.1 ml intradermally,Injection Indocyanine green in sterile water 2 ml intradermally
Sponsors
Department of surgery Faculty of medicine Ramathibodi Hospital , Mahidol university , Bangkok , Thai
Eligibility
Sex/Gender
All
Age
10 Years to 90 Years
Inclusion criteria
Inclusion criteria: Eligible patients were those with locally advanced breast cancer (T2–4, N1–2) who received neoadjuvant treatment, with tissue pathology confirmed carcinoma
Exclusion criteria
Exclusion criteria: Patients who had surgical biopsy or surgery that involved the axillary regions, and those with a history of allergy to ICG, isosulfan blue, or radioisotope were excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| number of sentinel lymph node biopsy using blue dye , radioisotrope , ICG 15 minutes after injection blue dye and ICG , 60 mins after inject radioisotrope Statistical analysis of patients’ characteristic data was done using descriptive statistics. The i | — |
Secondary
| Measure | Time frame |
|---|---|
| accuracy of sentinel lymph node biopsy in post neoadjuvant treatment breast cance 15 minutes after injection blue dye and ICG , 60 mins after inject radioisotrope Statistical analysis of patients’ characteristic data was done using descriptive statistics. The i | — |
Countries
Thailand
Contacts
Public Contacttanet chatmongkonwat
Ramathibodi Hospital
Outcome results
None listed