Effect of different doses of steroid on respiratory distress syndrome in moderate to late preterm neonates born between 320-366 weeks of gestation: A randomized controlled trial

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

TCTR

Registry ID

TCTR20200729002

Enrollment

380

Registered

2020-07-29

Start date

2020-12-20

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

neonatal RDS dexamethasone dosage neonatal RDS

Interventions

Comparison low dose of steroid, 4 mg, to prevent neonatal RDS,Comparison low dose of steroid, 5 mg, to prevent neonatal RDS

Dexamethasone 5 mg,Dexamethasone 6 mg

Eligibility

Sex/Gender

Female

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: pregnant women with gestational age 32-36+6 weeks of gestation with preterm labour (including singleton and twins pregnancy) and decide to participate in the study

Exclusion criteria

Exclusion criteria: Pregnant women who have previously received steroid therapy before 32 weeks of gestation, pregnant women with gestational diabetes and have steroid resistance will beexcluded.

Design outcomes

Primary

Measure	Time frame
neonatal respiratory distress syndrome (RDS) 0-48 hours after delivery observe respiration pattern of newborn	—

Secondary

Measure	Time frame
maternal outcome 0-48 hours after delivery temperature, foul smell discharge	—

Countries

Thailand

Contacts

Public ContactSaifon Chawanpaiboon

Siriraj Hospital

saifon.cha@mahidol.ac.th024197000

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026