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Conditions
Interventions
vaginal erbium laser for 10 minutes every 4 weeks for 3 times,1 tab vaginal suppo OD for 12 days,
then 2 tabs per week for total duration 12 weeks
vaginal erbium laser ,local estrogen plus probiotic
Sponsors
Ratchadapisek sompotch Fund
Eligibility
Sex/Gender
Female
Age
45 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Natural postmenopause women (more than 12 months of amenorrheic period without other related organic pathologies) 2. Age 45-75 years 3. Women presenting with at least one clinical symptom of genitourinary syndrome of menopause(vaginal dryness, dyspareunia, itching, irritation)
Exclusion criteria
Exclusion criteria: 1. Receive treatment with vaginal moisturizers, vaginal lubricant, vaginal laser, systemic or local estrogens within 90 days before recruitment 2. Pelvic organ prolapse stage 3 or higher 3. BMI of more than 35 kg/m2 4. Vaginal infection within 30 days 5. Any type of vaginal surgery within 90 days
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vaginal Maturation Index 4,8,112 weeks Vaginal Maturation Index | — |
Secondary
| Measure | Time frame |
|---|---|
| patient symptoms(dryness, dyspareunia, ithching, irritation) 12 weeks Visual analogue scale,patient satisfation 12 weeks Visual analogue scale,vaginal health index (VHI) 12 weeks clinical evaluation,adverse effects 12 weeks Bleeding, infection, pain incidence | — |
Contacts
Public ContactKrasean Panyakamlerd
Chulalongkorn University
Outcome results
None listed