Symptomatic myoma uteri Myoma uteri
Conditions
Interventions
Depo-
medroxyprogesterone acetate,Bromocriptine drug
Active Comparator Drug,Active Comparator Drug
DMPA,Bromocriptine
Sponsors
none
Eligibility
Sex/Gender
Female
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1.Woman ages between 20-50 years old. 2.Myoma uteri confirmed by transvaginal ultrasound 3.Pelvic pain or abnormal uterine bleeding 4.Waiting for surgery or premenopausal woman 5.Woman who can reading and writing
Exclusion criteria
Exclusion criteria: 1.Heavy uterine bleeding that must have emergency treatment 2.Transvaginal ultrasound found other disease in pelvic organ such as ovarian cancer 3.Woman who take COC in 1 month or DMPA/implant in 3 months ago 4.Deny to taked transvaginal ultrasound 5.Pregnancy, lactation or fertility desires 6.Abnormal liver or kidney function 7.Ergot allergy 8.Bleeding disorder 9.Contraindication to bromocriptine including allergy, uncontrolled hypertension, pregnancy induced hypertension, myocardial infarction and severe psychological diseases. 10.Contraindication to DMPA including uncontrolled hypertension, severe cirrhosis or liver tumor, Kidney or vascular complication from DM , venous thrombosis, cerebrovascular or myocardial infarction, breast cancer and undiagnosed abnormal uterine bleeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pelvic pain by using VAS score or duration of abnormal uterine bleeding 12 weeks VAS score, Time table of abnormal uterine bleeding | — |
Secondary
| Measure | Time frame |
|---|---|
| size of the largest myoma uteri 12 weeks transvaginal ultrasound,uterine volume 12 weeks transvaginal ultrasound | — |
Contacts
Public ContactKuntima Kantawee
Faculty of Medicine, Khon Kaen University
Outcome results
None listed