Healthy Thai volunteers age between 35-
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Healthy male and female aged 35-55 years of all skin type (normal, dry, oily and combination skin) 2. Having dull skin, pigmentary dark spots and acne lesion on the face 3. Having type II to V facial skin color according to Fitzpateick Scale 4. Having experience of using counter brand skincare product
Exclusion criteria
Exclusion criteria: 1. Having a history of hyperallergic reaction 2. Having a history of allergy to any whitening and anti-melasma products or any counter brand cosmetic products 3. Having a history of skin eczema, psoriasis within 6 months before enter the study 4. Having a history of using steriod, antibiotic, NSAIDs and antihistamine within 3 days before enter the study 5. Having a history of using any topical medicine on the face in the last 3 weeks before enter the study 6. Having chronic disease and continuous taking medicines 7. Having a history of any type of skin cancer within 1 year before enter the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin color week 0, 2, 4, 6 and 8 Chromameter | — |
Secondary
| Measure | Time frame |
|---|---|
| Melanin and erythema values week 0, 2, 4, 6 and 8 Mexameter | — |
Countries
Thailand
Contacts
Cosmetics and natural products research center, Faculty of Pharmaceutical Sciences, NU