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Effect of perioperative immune-enhancing diet in head and neck cancer surgery patients: a randomized controlled trial

Effect of perioperative immune-enhancing diet in head and neck cancer surgery patients: a randomized controlled trial

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20200624003
Enrollment
100
Registered
2020-06-24
Start date
2017-09-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head and neck cancer patients undergoing major surgery Head and neck cancer&#44

Interventions

mune&#44
an immune&#45
enhancing diet ,Hospital prepared blenderized diet&#44
regularly used in hospitalized patient
mune ,Hospital blenderized diet

Sponsors

None
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Head and neck cancer patients undergoing major surgery Age 18-75 years

Exclusion criteria

Exclusion criteria: Previous head and neck surgery Previous head and neck radiation Poor liver function(Total bilirubin > 3.5 mg/dl) Poor renal function (Serum creatinine > 2.5 mg/dl) Underlying immunodeficiency or taking immunosuppressive drug Allergy to arginine, glutamine,fish oil, or soy protein Pregnancy or breast feeding

Design outcomes

Primary

MeasureTime frame
serum albumin, prealbumin, transferrin, total lymphocyte count 1st, 7th, and 14th days after the operation Albumin (g/dl), Prealbumin (mg/dl), Transferrin (mg/dl), Total lymphocyte count (cells/mm2)

Secondary

MeasureTime frame
Surgical site infection rate, length of hospital stay 1 month, until discharge date percent of patients with surgical site infection, days of hospitalization

Countries

Thailand

Contacts

Public ContactPichit Sittitrai

Department of Otolaryngology, Faculty of Medicine, Chiang Mai University

psittitrai@yahoo.com6653935564

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026