Hypovitaminosis D in children with epilepsy
Conditions
Interventions
No additional supplements given to this group.,All subjects in this group were given daily oral 600 IU vitamin D supplementation for the three months of study period.
Vitamin D un-
supplemented,Vitamin D supplemented
Sponsors
Maulana Azad Medical College
Eligibility
Sex/Gender
All
Age
2 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. Fulfilling definition of epilepsy, as per International League Against Epilepsy (ILAE, 2014): - • At least two unprovoked (or reflex) seizures occurring more than 24 hours apart. • One unprovoked (or reflex) seizure and a probability of further seizures similar to the general recurrence risk (at least 60%) after two unprovoked seizures, occurring over the next 10 years. • Diagnosis of an Epilepsy syndrome. 2. Planned to be started on sodium valproate monotherapy. 3. Baseline serum 25-hydroxy vitamin D level >20 ng/mL.
Exclusion criteria
Exclusion criteria: 1. Known chronic renal or liver disease. 2. Non-ambulatory and/or tube-fed. 3. Received vitamin D supplementation in the last 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum 25-hydroxy vitamin D level 3 months of intervention Electrochemoluminescence binding assay (ECLIA) | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum Parathyroid hormone 3 months of intervention Electrochemiluminescence binding assay (ECLIA),Serum calcium 3 months of intervention SPECTROPHOTOMETRY,Ionized calcium 3 months of intervention Ion Selective Electrode (ISE),Serum Phosphate 3 months of intervention Photometric Assay,Alkaline Phosphate 3 months of intervention Calorimetric assay | — |
Countries
INDIA
Contacts
Public ContactSRUTI MISHRA
MAULANA AZAD MEDICAL COLLEGE
Outcome results
None listed