Pain evaluation during core needle biopsy between sodium bicarbonate-buffer lidocaine and Lidocaine alone ; A Randomized controlled trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

TCTR

Registry ID

TCTR20200619003

Enrollment

100

Registered

2020-06-19

Start date

2020-09-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain problem during core needle biopsy can relive by lidocaine buffer with sodiumbicarbonate by alkalization mathod

Interventions

Core needle biopsy with lidocain buffer with sodium bicarbonate ratio 10:1 total volumn 10mL (injection 3mL for skin and subcutaneous and 7mL for parenchymal lesion),Core needle biopsy with lidocain b

Active Comparator Drug,No Intervention Drug

lidocaine buffer with sodium bicarbonate (10:1) ,lidocaine with NSS (10:1)

Eligibility

Sex/Gender

All

Age

8 Years to No maximum

Inclusion criteria

Inclusion criteria: Patient with bone tumor/soft tissue tumor at extremities Patient with bone tumor/soft tissue tumor size 5-15 cm. Patient with age upper than 8 years

Exclusion criteria

Exclusion criteria: Patient who got core needle biopsy before Patient with history of drug allergy Pregnant patient

Design outcomes

Primary

Measure	Time frame
Mean Visual analogue scale from two groups Pre procedure, during injection, during biopsy, post biopsy Visual analogue scale	—

Secondary

Measure	Time frame
complication from study In 2 weeks post procedure number of complication	—

Contacts

Public ContactPrysatha Sarabhorn

Department of Orthopedics, Faculty of Medicine Prince of Songkla University

Prysatha@gmail.com+66887840240

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026

Pain evaluation during core needle biopsy between sodium bicarbonate&#45;buffer lidocaine and Lidocaine alone ; A Randomized controlled trial